--- title: "Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico" description: Discover the potential therapeutic benefits of Oxyspora paniculata through in silico analysis highlighting its neuropharmacological, antidiarrheal, and thrombolytic activities. --- [![logo2](https://www.journalbep.com/hs-fs/hubfs/logo2.jpeg?width=352&height=353&name=logo2.jpeg "logo2")](https://journalbep.com/) - [Home](https://www.journalbep.com) - Articles - - [All Articles](https://www.journalbep.com/all-articles) - 2023 - 2024 - 2025 - [Forthcoming Issues](https://www.journalbep.com/forthcoming-issue) - [Current Issue](https://www.journalbep.com/current-issue) - [All Issues](https://www.journalbep.com/all-issues) - Article Year Wise - [2023](https://www.journalbep.com/articles/2023) - [2024](https://www.journalbep.com/articles/2024) - [2025](https://www.journalbep.com/volume3-issue1) - Information - - [Advertising Policy](https://www.journalbep.com/advertising-policy) - [Open Access](https://www.journalbep.com/open-access) - [Editors](https://www.journalbep.com/editors) - [Reviewers](https://www.journalbep.com/reviewers) - [Authors](https://www.journalbep.com/authors) - [Announcements](https://www.journalbep.com/announcements) - About - - [Aim and Scope](https://www.journalbep.com/aim-and-scope) - [Chief Editor](https://www.journalbep.com/chief-editor) - [Editorial Board](https://www.journalbep.com/editorial-board) - [Fees](https://www.journalbep.com/fees-payments) - [Home](https://www.journalbep.com) - Articles - - [All Articles](https://www.journalbep.com/all-articles) - 2023 - 2024 - 2025 - [Forthcoming Issues](https://www.journalbep.com/forthcoming-issue) - [Current Issue](https://www.journalbep.com/current-issue) - [All Issues](https://www.journalbep.com/all-issues) - Article Year Wise - [2023](https://www.journalbep.com/articles/2023) - [2024](https://www.journalbep.com/articles/2024) - [2025](https://www.journalbep.com/volume3-issue1) - Information - - [Advertising Policy](https://www.journalbep.com/advertising-policy) - [Open Access](https://www.journalbep.com/open-access) - [Editors](https://www.journalbep.com/editors) - [Reviewers](https://www.journalbep.com/reviewers) - [Authors](https://www.journalbep.com/authors) - [Announcements](https://www.journalbep.com/announcements) - About - - [Aim and Scope](https://www.journalbep.com/aim-and-scope) - [Chief Editor](https://www.journalbep.com/chief-editor) - [Editorial Board](https://www.journalbep.com/editorial-board) - [Fees](https://www.journalbep.com/fees-payments) Search Search - [CONTACT US](https://www.journalbep.com/editorial-board) - [CONTACT US](https://www.journalbep.com/editorial-board) Search Search Original article Open access | J. Bio. Exp. Pharm. 2024, 2(2), 60-70. | https://doi.org/10.62624/JBEP00.0018 Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico Md. Sifat Foysal, Md. Riaz Hossain, Md. Nishan Shorif, Tasneem Jahan, Nahida Akter, Ayesha Siddika Farha, Dr. Mohammed Aktar Sayeed --- ## Abstract The application of supplementary herbal medicines has lately expanded in an effort to discover viable alternative therapies that lessen the side effects of chemical pharmaceuticals. Oxyspora paniculata is a rich source of phytochemicals with pharmacological action; therefore, it may have health advantages. This current research was performed to analyze the in silico evaluation of phytoconstituents present in Oxyspora paniculata for neuropharmacological, antidiarrheal, and thrombolytic activity. In silico activity of the isolated constituents for antioxidant activity was carried out by PyRx AutoDock Vina, and the protein-ligand interactions were examined using BIOVIA Discovery Studio Visualizer. ADME analysis was performed utilizing the SwissADME free online web server, and a toxicology study was done using the admetSAR online server. In the computational approach, among all the proteins, a docking score was found ranging from −4.6 to −10.3 kcal/mol. Besides, all the compounds were found safe in the ADME/T study. The absorption, distribution, metabolism, excretion/toxicity evaluation of phytoconstituents assures that they have obeyed Lipinski’s guideline of five, suggesting their safe consumption. The results of our scientific research validate the suitability of this plant as an alternative source of novel therapeutics. It was determined that Oxyspora paniculata contained active phytochemicals, which might provide a variety of pharmacological uses as a hidden source of substances with significant medicinal value. This needs more investigation in order to identify secondary metabolites that can be used to treat various illnesses.   --- [Read Full Text](https://www.journalbep.com/hubfs/Articles%20File%20-%20vol2%20issue%202/Article%204%20final.pdf) [Download Pdf](https://www.journalbep.com/hubfs/Articles%20File%20-%20vol2%20issue%202/Article%204%20final.zip) Cite × ### Cite - **MLA**: Md. Sifat Foysal, Md. Riaz Hossain, Md. Nishan Shorif, Tasneem Jahan, Nahida Akter, Ayesha Siddika Farha, Dr. Mohammed Aktar Sayeed. "Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico." *J. Bio. Exp. Pharm* 2.2 (2024): 60-70. - **APA**: Md. Sifat Foysal, Md. Riaz Hossain, Md. Nishan Shorif, Tasneem Jahan, Nahida Akter, Ayesha Siddika Farha, Dr. Mohammed Aktar Sayeed, (2024). Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico. *J. Bio. Exp. Pharm*, 2(2), 60-70. - **Chicago**: Md. Sifat Foysal, Md. Riaz Hossain, Md. Nishan Shorif, Tasneem Jahan, Nahida Akter, Ayesha Siddika Farha, Dr. Mohammed Aktar Sayeed. "Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico." *J. Bio. Exp. Pharm* 2, no. 2 (2024): 60-70. - **Harvard**: Md. Sifat Foysal, Md. Riaz Hossain, Md. Nishan Shorif, Tasneem Jahan, Nahida Akter, Ayesha Siddika Farha, Dr. Mohammed Aktar Sayeed, 2024. Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico. *J. Bio. Exp. Pharm*, 2(2), pp. 60-70. - **Vancouver**: Md. Sifat Foysal, Md. Riaz Hossain, Md. Nishan Shorif, Tasneem Jahan, Nahida Akter, Ayesha Siddika Farha, Dr. Mohammed Aktar Sayeed. Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico. *J. Bio. Exp. Pharm*. 2024;2(2): 60-70. BibTeX EndNote RefMan ##### [Current Issue ![Volume 3 - Issue 1](https://www.journalbep.com/hubfs/v2-i2.jpg) Volume 3 - Issue 1]({url={type=FILE,%20content_id=null,%20href=https://www.journalbep.com/hubfs/Journal%20of%20Biosciences%20and%20Experimental%20Pharmacology%2c%20Volume%203%20Issue%201%2c%202025-2.pdf,%20href_with_scheme=https://243687258.fs1.hubspotusercontent-na2.net/hubfs/243687258/Journal%20of%20Biosciences%20and%20Experimental%20Pharmacology%2c%20Volume%203%20Issue%201%2c%202025-2.pdf},%20open_in_new_tab=true,%20no_follow=false,%20sponsored=false,%20user_generated_content=false,%20rel=noopener}) ### Author Affiliation   ### Share Article [![logo2](https://www.journalbep.com/hs-fs/hubfs/logo2.jpeg?width=352&height=353&name=logo2.jpeg "logo2")](https://journalbep.com/) - [About us](https://www.journalbep.com/editorial-board) - [Aim and Scope](https://www.journalbep.com/aim-and-scope) - [Chief Editor](https://www.journalbep.com/chief-editor) - [Editorial Board](https://www.journalbep.com/editorial-board) - [Fees](https://www.journalbep.com/fees-payments) - [Articles](https://www.journalbep.com/articles) - [All Articles](https://www.journalbep.com/all-articles) - [Forthcoming Issues](https://www.journalbep.com/forthcoming-issue) - [Current Issue](https://www.journalbep.com/current-issue) - [All Issues](https://www.journalbep.com/all-issues) - [Information](https://www.example.com) - [Advertising Policy](https://www.journalbep.com/advertising-policy) - [Open Access](https://www.journalbep.com/open-access) - [Editors](https://www.journalbep.com/editors) - [Reviewers](https://www.journalbep.com/reviewers) - [Authors](https://www.journalbep.com/authors)   Copyright © 2025 - All rights reserved by JBEP ```json { "@context" : "https://schema.org", "@type" : "BlogPosting", "author" : { "@type" : "Person", "name" : "Ashraful Alam", "url" : "https://www.journalbep.com/articles/author/ashraful-alam" }, "dateModified" : "2025-10-14T04:05:16.771Z", "datePublished" : "2025-10-14T04:05:11.000Z", "headline" : "Unveiling the therapeutic profile of Oxyspora paniculata: Insights into neuropharmacological, antidiarrheal, and thrombolytic activities In Silico", "mainEntityOfPage" : { "@id" : "https://www.journalbep.com/articles/unveiling-the-therapeutic-profile-of-oxyspora-paniculata-insights-into-neuropharmacological-antidiarrheal-and-thrombolytic-activities-in-silico", "@type" : "WebPage" }, "publisher" : { "@type" : "Organization", "logo" : { "@type" : "ImageObject", "url" : "https://www.journalbep.com/hubfs/unnamed.png" } } } ```